产品货号：
Z25499
中文名称：
ROCK2抗体
英文名称：
Anti-ROCK2 Antibody (C-term)
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ROCK2 Antibody (C-term) |
| 指标别名 | KIAA0619;p164 ROCK 2;Rho kinase 2;ROCK2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | ROCK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This ROCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1346-1380 amino acids from the C-terminal region of human ROCK2. |
| 计算分子量 | 161kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.Involved in regulation of smooth muscle contraction,actin cytoskeleton organization,stress fiber and focal adhesion formation,neurite retraction,cell adhesion and motility via phosphorylation of ADD1,BRCA2,CNN1,EZR,DPYSL2,EP300,MSN,MYL9/MLC2,NPM1,RDX,PPP1R12A and VIM.Phosphorylates SORL1 and IRF4.Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation.Positively regulates the activation of p42/MAPK1-p44/MAPK3 and of p90RSK/RPS6KA1 during myogenic differentiation.Plays an important role in the timely initiation of centrosome duplication.Inhibits keratinocyte terminal differentiation.May regulate closure of the eyelids and ventral body wall through organization of actomyosin bundles.Plays a critical role in the regulation of spine and synaptic properties in the hippocampus.Plays an important role in generating the circadian rhythm of the aortic myofilament Ca (2+) sensitivity and vascular contractility by modulating the myosin light chain phosphorylation. |
| Uniprot ID | O75116 |
相关搜索：ROCK2抗体，ROCK2(C-term)多抗，Anti-ROCK2 Antibody (C-term)